Прагляд зыходнага тэксту старонкі Трамбін

{{GNF_Protein_box
 | image = 2c93.png
 | image_source = Трамбін у комплексе з інгібітарам
 | PDB =
{{Утоены
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}}
 | Name = Тромбин (фактор свертывания II)
 | HGNCid = 3535
 | Symbol = F2
 | AltSymbols =; PT
 | OMIM = 176930
 | ECnumber =  
 | Homologene = 426
 | MGIid = 88380
 | GeneAtlas_image1 = PBB_GE_F2_205754_at_tn.png
 <!-- The Following entry is a time stamp of the last bot update.  It is typically hidden data -->
 | DateOfBotUpdate = 07:23, 9 October 2007 (UTC)
 | Function = {{GNF_GO|id=GO:0003809 |text = thrombin activity}} {{GNF_GO|id=GO:0005102 |text = receptor binding}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} 
 | Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}} {{GNF_GO|id=GO:0005625 |text = soluble fraction}} 
 | Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0006915 |text = apoptosis}} {{GNF_GO|id=GO:0006919 |text = caspase activation}} {{GNF_GO|id=GO:0006953 |text = acute-phase response}} {{GNF_GO|id=GO:0007260 |text = tyrosine phosphorylation of STAT protein}} {{GNF_GO|id=GO:0007262 |text = STAT protein nuclear translocation}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007596 |text = blood coagulation}} {{GNF_GO|id=GO:0009611 |text = response to wounding}} {{GNF_GO|id=GO:0030168 |text = platelet activation}} {{GNF_GO|id=GO:0030193 |text = regulation of blood coagulation}} {{GNF_GO|id=GO:0042730 |text = fibrinolysis}} 
 | Hs_EntrezGene = 2147
 | Hs_Ensembl = ENSG00000180210
 | Hs_RefseqProtein = NP_000497
 | Hs_RefseqmRNA = NM_000506
 | Hs_GenLoc_db =  hg18
 | Hs_GenLoc_chr = 11
 | Hs_GenLoc_start = 46697331
 | Hs_GenLoc_end = 46717631
 | Hs_Uniprot = P00734
 | Mm_EntrezGene = 14061
 | Mm_Ensembl = ENSMUSG00000027249
 | Mm_RefseqmRNA = NM_010168
 | Mm_RefseqProtein = NP_034298
 | Mm_GenLoc_db =  mm8
 | Mm_GenLoc_chr = 2
 | Mm_GenLoc_start = 91426157
 | Mm_GenLoc_end = 91437253
 | Mm_Uniprot = Q3TJ94
}}

'''Трамбін''', '''трамбаза''' (фактар згусання II) — найважнейшы кампанент сістэмы згусання [[кроў|крыві]] чалавека і жывёл. Трамбін (КФ 3.4.21.5) адносіцца да ферментаў класа гідралаз (серынавая пратэаза), каталізуе гідроліз пептыдных сувязяў, утвораных рэшткамі [[аргінін]]у і [[лізін]]у (валодае абмежаванай субстратнай спецыфічнасцю).

== Літаратура ==
* {{Крыніцы/БелЭн|15|Трамбі́н, трамбаза, фібрын-фермент||503}}
* {{БСЭ3|Тромби́н|26|241|аўтар=Баскова И. П.}}

{{Бібліяінфармацыя}}
[[Катэгорыя:Гідралазы]]
[[Катэгорыя:Бялкі чалавека]]